AL-9
Based on 1 Customer Validation
AL-9 is a inhibitor of PI4KIIIα, with the IC50 of 0.57 μM, that can inhibit HCV replication.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.68%
- CAS 番号: 869218-90-6
- 分子式: C23H22N4O3
- 分子量:402.45
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Oxygen Sensing Compound Library
HY-L045
-
Glycolysis Compound Library
HY-L058
-
Cytoskeleton Compound Library
HY-L060
-
Anti-Hepatitis C Virus Compound Library
HY-L073
-
Anti-Pancreatic Cancer Compound Library
HY-L077
-
Anti-Cancer Metabolism Compound Library
HY-L083
-
Anti-Obesity Compound Library
HY-L087
-
Glucose Metabolism Compound Library
HY-L092
-
Cancer Stem Cells Compound Library
HY-L135
-
Membrane Protein-targeted Compound Library
HY-L149
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Anti-Infection Compound Library
HY-L002
-
Kinase Inhibitor Library
HY-L009
-
PI3K/Akt/mTOR Compound Library
HY-L015
-
Antiviral Compound Library
HY-L027
-
Anti-Aging Compound Library
HY-L034
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | EC50 |
0.29 μM
Compound: AL-9
|
Antiviral activity against HCV genotype 1b infected in human Huh7.5 cells assessed as inhibition of viral replication after 72 hrs by real time PCR analysis
Antiviral activity against HCV genotype 1b infected in human Huh7.5 cells assessed as inhibition of viral replication after 72 hrs by real time PCR analysis
|
[PMID: 24900715] |
| Sf9 | IC50 |
0.57 μM
Compound: AL-9
|
Inhibition of PI4K3alpha catalytic domain (unknown origin) expressed in baculovirus-infected Sf9 cells using PI:PS as substrate incubated for 10 mins followed by substrate addition measured after 1 hr by ADP-Glo kinase assay
Inhibition of PI4K3alpha catalytic domain (unknown origin) expressed in baculovirus-infected Sf9 cells using PI:PS as substrate incubated for 10 mins followed by substrate addition measured after 1 hr by ADP-Glo kinase assay
|
[PMID: 24900715] |
| Sf9 | IC50 |
3.08 μM
Compound: AL-9
|
Inhibition of PI4K3beta (unknown origin) expressed in baculovirus-infected Sf9 cells using PI:PS as substrate incubated for 10 mins followed by substrate addition measured after 1 hr by ADP-Glo kinase assay
Inhibition of PI4K3beta (unknown origin) expressed in baculovirus-infected Sf9 cells using PI:PS as substrate incubated for 10 mins followed by substrate addition measured after 1 hr by ADP-Glo kinase assay
|
[PMID: 24900715] |
化学情報
-
CAS 番号 869218-90-6
-
性状 Solid
-
分子量 402.45
-
分子式 C23H22N4O3
-
Color Light yellow to yellow
-
SMILES
OCC1=CC=C(C2=CC3=C(NC4=CC=C(N5CCOCC5)C=C4)N=CN=C3C=C2)O1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 5 mg/mL (12.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4848 mL | 12.4239 mL | 24.8478 mL | 62.1195 mL |
| 5 mM | 0.4970 mL | 2.4848 mL | 4.9696 mL | 12.4239 mL | |
| 10 mM | 0.2485 mL | 1.2424 mL | 2.4848 mL | 6.2120 mL |
AL-9 関連分類
HY-118525 関連分類
Powered by Bioz