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Belrestotug

(別名: EOS-448; EOS884448; GSK4428859A)
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Based on 1 Customer Validation

Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Belrestotug
  • Experimental Validation Results for Belrestotug
  • Experimental Validation Results for Belrestotug
  • Belrestotug Chemical Structure
    Belrestotug 構造式
CAS 番号: 2574438-65-4
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Belrestotug on AHC2 biosensor, can bind TIGIT Protein, Human (120a.a, HEK293, His, HY-P70624) with an affinity constant of 6.401E-10 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 FaDu cells with Belrestotug (HY-P990032, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Belrestotug Chemical Structure
    1/16
  • Belrestotug
  • Loaded Belrestotug on AHC2 biosensor, can bind TIGIT Protein, Human (120a.a, HEK293, His, HY-P70624) with an affinity constant of 6.401E-10 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 FaDu cells with Belrestotug (HY-P990032, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).