Biotin-Thalidomide
Based on 1 Customer Validation
Biotin-Thalidomide is a biotin-conjugated Thalidomide (HY-14658) for binding to CRBN. Biotin-Thalidomide can be used to synthesize PROTAC .
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.45%
- CAS 番号: 2230857-87-9
- 分子式: C44H64N8O13S
- 分子量:945.09
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
E3 Ligase Ligand-Linker Conjugates アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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Cereblon |
化学情報
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CAS 番号 2230857-87-9
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性状 Solid
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分子量 945.09
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分子式 C44H64N8O13S
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Color Off-white to yellow
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SMILES
O=C1C2=C(OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]3[C@]4([H])[C@](NC(N4)=O)([H])CS3)=O)=O)=O)=O)C=CC=C2C(N1C5C(NC(CC5)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
Methanol : 125 mg/mL (132.26 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 1.0581 mL | 5.2905 mL | 10.5810 mL | 26.4525 mL |
| 5 mM | 0.2116 mL | 1.0581 mL | 2.1162 mL | 5.2905 mL | |
| 10 mM | 0.1058 mL | 0.5291 mL | 1.0581 mL | 2.6453 mL | |
| 15 mM | 0.0705 mL | 0.3527 mL | 0.7054 mL | 1.7635 mL | |
| 20 mM | 0.0529 mL | 0.2645 mL | 0.5291 mL | 1.3226 mL | |
| 25 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0581 mL | |
| 30 mM | 0.0353 mL | 0.1764 mL | 0.3527 mL | 0.8818 mL | |
| 40 mM | 0.0265 mL | 0.1323 mL | 0.2645 mL | 0.6613 mL | |
| 50 mM | 0.0212 mL | 0.1058 mL | 0.2116 mL | 0.5291 mL | |
| 60 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4409 mL | |
| 80 mM | 0.0132 mL | 0.0661 mL | 0.1323 mL | 0.3307 mL | |
| 100 mM | 0.0106 mL | 0.0529 mL | 0.1058 mL | 0.2645 mL |
Biotin-Thalidomide 関連分類
HY-145152 関連分類
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