BMS-317180
BMS-317180 is an orally active and potent growth hormone secretagogue receptor (GHS-R) agonist (EC50=7.9 nM). BMS-317180 stimulates endogenous growth hormone (GH) release. BMS-317180 is promising for research of age-related frailty, osteoporosis, and cancer cachexia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 295337-71-2
- 分子式: C21H33N7O5
- 分子量:463.53
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| H4 | EC50 |
1.9 nM
Compound: 2, BMS-317180
|
Intrinsic activity at human GHS receptor in H4 glioma cells assessed by measuring intracellular calcium concentration by FLIPR assay
Intrinsic activity at human GHS receptor in H4 glioma cells assessed by measuring intracellular calcium concentration by FLIPR assay
|
[PMID: 17973363] |
| H4 | EC50 |
1.9 nM
Compound: 4, BMS-317180
|
Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assay
Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assay
|
[PMID: 18378446] |
化学情報
-
CAS 番号 295337-71-2
-
分子量 463.53
-
分子式 C21H33N7O5
-
SMILES
O=C(NCCCCO)OCCN1N=NN=C1[C@@H](COCC2=CC=CC=C2)NC(C(N)(C)C)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Powered by Bioz