CAY10535
CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 945716-28-9
- 分子式: C18H21N3O7S
- 分子量:423.44
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
|
TP Receptor |
FP Receptor |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
1970 nM
Compound: 9ag
|
Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
|
[PMID: 17630727] |
| HEK293 | IC50 |
99 nM
Compound: 9ag
|
Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization
|
[PMID: 17630727] |
体外実験
CAY10535 (10 μM) significantly inhibits PGF2α (1 μM) and/or capsaicin (2 μM) induced coronary rings contractions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 945716-28-9
-
分子量 423.44
-
分子式 C18H21N3O7S
-
SMILES
O=S(C1=CC([N+]([O-])=O)=CC=C1OC2=CC=CC(OC)=C2)(NC(NC(C)(C)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)