CDK9-IN-26
CDK9-IN-26 (compound 1is a CDK9 inhibitor (IC50=0.18 μM). .
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C17H14N4O2
- 分子量:306.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
IC50: 0.18 μM (CDK9)[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38564299] |
| K562 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
|
[PMID: 38564299] |
| MCF7 | IC50 |
11.62 μM
Compound: 63; Cpd 1d
|
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 38564299] |
化学情報
-
分子量 306.32
-
分子式 C17H14N4O2
-
SMILES
COC1=CC=C(NC2=C(C3=COC=C3)N=C4C=NC=CN42)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)