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CDP-484

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Based on 1 Customer Validation

CDP-484 is a CHO-expressed human antibody that targets IL-1b. CDP-484 is comprised of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.74 kDa. The isotype control for CDP-484 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

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  • 純度: 99.34%
  • 分子量:145.74 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for CDP-484
  • Experimental Validation Results for CDP-484
  • CDP-484 Chemical Structure
    CDP-484 構造式
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609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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  • 1/16

    Flow Cytometry analysis of HepG2 cells with CDP-484 (HY-P990563，red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa(HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized IL-1B-N-His can bind CDP-484. The EC50 for this effect is 26.43 ng/mL.

  • CDP-484 Chemical Structure
    1/16
  • CDP-484
  • Flow Cytometry analysis of HepG2 cells with CDP-484 (HY-P990563，red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa(HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized IL-1B-N-His can bind CDP-484. The EC50 for this effect is 26.43 ng/mL.