Copy Link Print Information

Cevostamab

(別名: BFCR 4350A; RG 6160; RO 7187797)
カスタマーレビュー

Based on 1 Customer Validation

Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度 : 99.00%
  • CAS 番号: 2249888-53-5
  • 分子量:146.19 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Experimental Validation Results for Cevostamab
  • Cevostamab Chemical Structure
    Cevostamab 構造式
CAS 番号: 2249888-53-5
容量
価格（税別）
在庫状況
数量
Amount: USD 0.00
Please select quantity
or
or

* アイテムを追加する前、数量をご選択ください

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Cevostamab おすすめ製品:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
  • 生物活性
  • 化学情報
  • 純度とドキュメンテーション
  • 参考文献
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Keywords

MOQ
Minimum order quantity
100 mg

お問い合わせ 在庫あり

Other size
お問い合わせ
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress ログイン
Register
Sign in to MedChemExpress
新規会員登録

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Cevostamab on AHC2 biosensor, can bind FcRH5/FcRL5 Protein, Human (HEK293, His, HY-P700302) with an affinity constant of 1.605E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells labeling FcRH5 with Cevostamab (HY-P99601, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Loaded Cevostamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 3.265E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells labeling CD3 with Cevostamab (HY-P99601, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Cevostamab Chemical Structure
    1/16
  • Cevostamab
  • Loaded Cevostamab on AHC2 biosensor, can bind FcRH5/FcRL5 Protein, Human (HEK293, His, HY-P700302) with an affinity constant of 1.605E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HepG2 cells labeling FcRH5 with Cevostamab (HY-P99601, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • Loaded Cevostamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 3.265E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Jurkat cells labeling CD3 with Cevostamab (HY-P99601, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).