CHL2310
Based on 1 Customer Validation
CHL2310 is the inhibitor for CYP46A1 with an IC50 of 0.11 nM, and a Kd of 0.37 nM. CHL2310 can cross blood-brain barrier. CHL2310 can be used as a PET imaging agent, when labeled with radioactive 18F.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.45%
- 分子式: C16H13F4N3O2
- 分子量:355.29
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: CYP46A1 (0.11 nM)
Kd: CYP46A1 (0.37 nM)
化学情報
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性状 Solid
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分子量 355.29
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分子式 C16H13F4N3O2
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Color White to off-white
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SMILES
O=C(N1CCC2=C1C=C(C=C2C3=CN=CO3)C(F)(F)F)N4CC(C4)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (281.46 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8146 mL | 14.0730 mL | 28.1460 mL | 70.3651 mL |
| 5 mM | 0.5629 mL | 2.8146 mL | 5.6292 mL | 14.0730 mL | |
| 10 mM | 0.2815 mL | 1.4073 mL | 2.8146 mL | 7.0365 mL | |
| 15 mM | 0.1876 mL | 0.9382 mL | 1.8764 mL | 4.6910 mL | |
| 20 mM | 0.1407 mL | 0.7037 mL | 1.4073 mL | 3.5183 mL | |
| 25 mM | 0.1126 mL | 0.5629 mL | 1.1258 mL | 2.8146 mL | |
| 30 mM | 0.0938 mL | 0.4691 mL | 0.9382 mL | 2.3455 mL | |
| 40 mM | 0.0704 mL | 0.3518 mL | 0.7037 mL | 1.7591 mL | |
| 50 mM | 0.0563 mL | 0.2815 mL | 0.5629 mL | 1.4073 mL | |
| 60 mM | 0.0469 mL | 0.2346 mL | 0.4691 mL | 1.1728 mL | |
| 80 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8796 mL | |
| 100 mM | 0.0281 mL | 0.1407 mL | 0.2815 mL | 0.7037 mL |
CHL2310 関連分類
HY-172205 関連分類
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