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製品番号: HY-N0609

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Cinnamaldehyde

3 Cited Publications

カスタマーレビュー

Based on 3 publication(s) in Google Scholar

Cinnamaldehyde is a major and a bioactive compound isolated from the leaves of Cinnamomum osmophloeum kaneh. Cinnamaldehyde is a cytokine production inhibitor. Cinnamaldehyde has anti-bacteria, anti-oxidation, and anti-inflammatory properties.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: ≥95.0%
CAS 番号: 104-55-2
分子式: C₉H₈O
分子量:132.16

保管条件:

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Cinnamaldehyde 構造式

CAS 番号: 104-55-2

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Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	6.5 μM Compound: 15	Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levels Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levels	[PMID: 20356305]
CHO	EC₅₀	61 μM Compound: CA	Agonist activity at mouse TRPA1 expressed in CHO cells assessed as increase in calcium influx by Fluo-3 based FLIPR analysis Agonist activity at mouse TRPA1 expressed in CHO cells assessed as increase in calcium influx by Fluo-3 based FLIPR analysis	[PMID: 30878828]
HCT-8	IC₅₀	15.6 μM Compound: 12; CA	Antiproliferative activity against human HCT8 cells after 72 hrs in presence of aspirin by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs in presence of aspirin by MTT assay	[PMID: 30037494]
HCT-8	IC₅₀	29.4 μM Compound: 12; CA	Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 30037494]
HEK293	EC₅₀	51.4 μM Compound: CA 3	Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count	[PMID: 19945872]
HEK293	EC₅₀	9 μM Compound: CA	Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay	[PMID: 30878828]
RAW264.7	IC₅₀	43 μM Compound: CA	Inhibition of NF-kappaB transfected in LPS-stimulated mouse RAW264.7 cells Inhibition of NF-kappaB transfected in LPS-stimulated mouse RAW264.7 cells	[PMID: 18823786]

体外実験

Cinnamaldehyde inhibits ROS release and the activation of MAPKs as well as pro-inflammatory cytokines expression within TLRs activated cultured monocytes/macrophages^[1]
. Cinnamaldehyde induces apoptosis by mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells, and induces apoptosis in human hepatoma cells through activation of the proapoptotic Bcl-2 family proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 104-55-2
性状 Liquid (Density: 1.05 g/cm³)
分子量 132.16
分子式 C₉H₈O
Color Colorless to yellow
SMILES

O=CC=CC=1C=CC=CC1
Structure Classification
- Others
Initial Source
- Plants
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Publications (3)

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Phytomedicine

Cinnamaldehyde activates AMPK/PGC-1α pathway via targeting GRK2 to ameliorate heart failure. [Abstract]

2024 Jul 20:133:155894. PMID: 39089090
Biol Reprod

Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet induced obese rats through TRPA1-mediated cl- and HCO3- secretion. [Abstract]

2023 Jul 11;109(1):53-64. PMID: 37154585
Patent

US11033516.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Chao LK, et al. Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling. Food Chem Toxicol. 2008;46(1):220‐231. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Cinnamaldehyde

3 Cited Publications

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生物活性
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化学情報
Publications (3)
純度とドキュメンテーション
参考文献

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Cinnamaldehyde

MedChemExpress（MCE）の使用を引用している文献 Cinnamaldehyde

生物活性

化学情報

Publications (3)

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Cinnamaldehyde 関連分類

HY-N0609 関連分類