Coronalolide
Coronalolide is a natural triterpene with anticancer effects. Coronalolide exhibits a broad cytotoxic activity for human breast (BT474), gastric (KATO-3), lung (CHAGO), colon (SW-620), and liver (Hep-G2) cancer cell lines, with IC50 values of 6.59 µg/mL, 5.85 µg/mL, 5.42 µg/mL, 4.98 µg/mL, and 6.41 µg/mL, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 268214-51-3
- 分子式: C30H42O5
- 分子量:482.65
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BT-474 | IC50 |
6.59 μg/mL
Compound: 7
|
Cytotoxicity against human BT474 cells after 3 days by MTT assay
Cytotoxicity against human BT474 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| HepG2 | IC50 |
6.41 μg/mL
Compound: 7
|
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
Cytotoxicity against human HepG2 cells after 3 days by MTT assay
|
[PMID: 19456120] |
| SW-620 | IC50 |
4.98 μg/mL
Compound: 7
|
Cytotoxicity against human SW620 cells after 3 days by MTT assay
Cytotoxicity against human SW620 cells after 3 days by MTT assay
|
[PMID: 19456120] |
化学情報
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CAS 番号 268214-51-3
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分子量 482.65
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分子式 C30H42O5
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SMILES
OC(CC[C@@]12[C@]3([C@](C[C@](O4)([H])[C@@]2([H])C(C4=O)=C)([H])[C@]5([C@@](C)([C@]([C@H](C)CC/C=C(C)/C=O)([H])CC5)CC3)C)C1)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)