Cytembena
Based on 1 Customer Validation
Cytembena is inhibitor for replicative DNA synthesis, purine synthesis and tetrahydrofolate formylase activity. Cytembena ameliorates ovarian or breast cancer, relieves the pain from skeletal metastases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.53%
- CAS 番号: 21739-91-3
- 分子式: C11H8BrNaO4
- 分子量:307.07
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 21739-91-3
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性状 Solid
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分子量 307.07
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分子式 C11H8BrNaO4
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Color Light yellow to yellow
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SMILES
O=C(O[Na])/C=C(Br)\C(C1=CC=C(C=C1)OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 50 mg/mL (162.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Falkson HC, et al., Phase II trial of cytembena in patients with advanced ovarian and breast cancer. Cancer Treat Rep. 1976 Nov;60(11):1655-8. [Content Brief]
[2]. Berger NA, et al., Description of a permeable eukaryotic cell system to study agents affecting DNA synthesis: demonstration that cytembena is a direct inhibitor of replicative DNA synthesis. J Natl Cancer Inst. 1977 Apr;58(4):1167-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2566 mL | 16.2829 mL | 32.5659 mL | 81.4147 mL |
| 5 mM | 0.6513 mL | 3.2566 mL | 6.5132 mL | 16.2829 mL | |
| 10 mM | 0.3257 mL | 1.6283 mL | 3.2566 mL | 8.1415 mL | |
| 15 mM | 0.2171 mL | 1.0855 mL | 2.1711 mL | 5.4276 mL | |
| 20 mM | 0.1628 mL | 0.8141 mL | 1.6283 mL | 4.0707 mL | |
| 25 mM | 0.1303 mL | 0.6513 mL | 1.3026 mL | 3.2566 mL | |
| 30 mM | 0.1086 mL | 0.5428 mL | 1.0855 mL | 2.7138 mL | |
| 40 mM | 0.0814 mL | 0.4071 mL | 0.8141 mL | 2.0354 mL | |
| 50 mM | 0.0651 mL | 0.3257 mL | 0.6513 mL | 1.6283 mL | |
| 60 mM | 0.0543 mL | 0.2714 mL | 0.5428 mL | 1.3569 mL | |
| 80 mM | 0.0407 mL | 0.2035 mL | 0.4071 mL | 1.0177 mL | |
| 100 mM | 0.0326 mL | 0.1628 mL | 0.3257 mL | 0.8141 mL |