Daunomycinone
Based on 1 Customer Validation
Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.89%
- CAS 番号: 21794-55-8
- 分子式: C21H18O8
- 分子量:398.36
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
化学情報
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CAS 番号 21794-55-8
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性状 Solid
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分子量 398.36
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分子式 C21H18O8
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Color Orange to red
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SMILES
O=C(C1=CC=CC(OC)=C1C2=O)C3=C2C(O)=C4[C@H](C[C@](C(C)=O)(CC4=C3O)O)O
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別名
NSC-109351
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 100 mg/mL (251.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (647 KB)
- English - EN (647 KB)
- Français - FR (647 KB)
- Deutsch - DE (647 KB)
- Norwegian - NO (647 KB)
- Español - ES (647 KB)
- Swedish - SV (647 KB)
- Italian - IT (647 KB)
- Korean - KR (647 KB)
- Portuguese - PT (647 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Herman EH, et al. Modification of some of the toxic effects of daunomycin (NSC-82,151) by pretreatment with the antineoplastic agent ICRF 159 (NSC-129,943). Toxicol Appl Pharmacol. 1974 Mar;27(3):517-26. [Content Brief]
[2]. Tan C, et al. Daunomycin, an antitumor antibiotic, in the treatment of neoplastic disease. Clinical evaluation with special reference to childhood leukemia. Cancer. 1967 Mar;20(3):333-53. [Content Brief]
[4]. Aligiannis N, et al. Synthesis and cytotoxic activity of a new potent daunomycinone derivative. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3505-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5103 mL | 12.5515 mL | 25.1029 mL | 62.7573 mL |
| 5 mM | 0.5021 mL | 2.5103 mL | 5.0206 mL | 12.5515 mL | |
| 10 mM | 0.2510 mL | 1.2551 mL | 2.5103 mL | 6.2757 mL | |
| 15 mM | 0.1674 mL | 0.8368 mL | 1.6735 mL | 4.1838 mL | |
| 20 mM | 0.1255 mL | 0.6276 mL | 1.2551 mL | 3.1379 mL | |
| 25 mM | 0.1004 mL | 0.5021 mL | 1.0041 mL | 2.5103 mL | |
| 30 mM | 0.0837 mL | 0.4184 mL | 0.8368 mL | 2.0919 mL | |
| 40 mM | 0.0628 mL | 0.3138 mL | 0.6276 mL | 1.5689 mL | |
| 50 mM | 0.0502 mL | 0.2510 mL | 0.5021 mL | 1.2551 mL | |
| 60 mM | 0.0418 mL | 0.2092 mL | 0.4184 mL | 1.0460 mL | |
| 80 mM | 0.0314 mL | 0.1569 mL | 0.3138 mL | 0.7845 mL | |
| 100 mM | 0.0251 mL | 0.1255 mL | 0.2510 mL | 0.6276 mL |
Daunomycinone 関連分類
HY-114658 関連分類
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