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製品番号: HY-N18049

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Decussatin

Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 20882-69-3
分子式: C₁₆H₁₄O₆
分子量:302.28

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Decussatin 構造式

CAS 番号: 20882-69-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- Cellular Effect
- 体外実験
- 体内実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
C6	IC₅₀	100 μM Compound: 3	Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay Antiproliferative activity against rat C6 cells assessed as cell number after 48 hrs by crystal violet assay	[PMID: 18406151]

体外実験

Decussatin (8 mg/mL) shows no significant inhibitory activity against Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, and Staphylococcus aureus in in vitro antibacterial assays^[2].
Decussatin exhibits an inhibition rate of 78.0% against α-amylase at a concentration of 1 mg/mL, and its inhibitory activity at this concentration is superior to that of Acarbose (HY-B0089) at the same concentration^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

The crude hydromethanolic extract of Anthocleista vogelii-the source plant for Decussatin administration at 1 g/kg via oral gavage, once daily for 7 days-significantly reduces blood glucose levels in alloxan-induced diabetic albino Wistar rats. The stem bark extract achieves a peak blood glucose reduction rate of 69.68% on day 5, while the leaf extract reaches a peak reduction rate of 60.35% on day 7; both are more effective in lowering blood glucose than Glibenclamide (HY-15206)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 20882-69-3
分子量 302.28
分子式 C₁₆H₁₄O₆
SMILES

O=C1C2=C(OC3=CC=C(C(OC)=C13)OC)C=C(OC)C=C2O
Structure Classification
- Phenols
- Monophenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Alaribe C S, et al. Antimicrobial activities of hexane extract and decussatin from stembark extract of Ficus congensis[J]. International journal of molecular sciences, 2011, 12(4): 2750-2756.

[2]. Olubomehin O O, et al. In vivo and in vitro anti-diabetic activity of extracts of Anthoclestia vogelii Planch and isolation of Decussatin, a new α-amylase inhibitor from its stem bark and leaves[J]. Nigerian Journal of Biochemistry and Molecular Biology, 2022, 37(1): 9-16.

[3]. Jia J, et al. Preparative separation of methylswertianin, swerchirin and decussatin from the Tibetan medicinal plant Swertia mussotii using high-speed counter-current chromatography. Phytochem Anal. 2012;23(4):332-336. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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