Dextromilnacipran
Based on 1 Customer Validation
Dextromilnacipran ((1R,2S)-Milnacipran; F2696) is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran can be used for the research of depression, fibromyalgia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.90%
- CAS 番号: 96847-55-1
- 分子式: C15H22N2O
- 分子量:246.35
-
保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
GPCR/G Protein Compound Library
HY-L006
-
Neuronal Signaling Compound Library
HY-L013
-
FDA-Approved Drug Library
HY-L022
-
Drug Repurposing Compound Library
HY-L035
-
Orally Active Compound Library
HY-L061
-
Neurotransmitter Receptor Compound Library
HY-L062
-
FDA Approved & Pharmacopeial Drug Library
HY-L066
-
Anti-Alzheimer's Disease Compound Library
HY-L069
-
Neurodegenerative Disease-related Compound Library
HY-L086
-
Antidepressant Compound Library
HY-L108
-
Coagulation and Anti-coagulation Compound Library
HY-L136
-
Off-patent Drug Library
HY-L141
-
Antihypertensive Compound Library
HY-L145
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Drug Repurposing Compound Library Plus
HY-L035P
-
FDA-Approved Drug Library Plus
HY-L022P
-
FDA-Approved Drug Library Mini
HY-L022M
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Lactylation Compound Library
HY-L249
Adrenergic Receptor アイソフォーム固有の製品をすべて表示
More
生物活性
IC50: 3.4 μM (alpha-adrenergic receptor)
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
64 nM
Compound: rel-Milnacipran
|
Inhibition of human SERT expressed in CHO cell membranes assessed as reduction in [3H]serotonin uptake preincubated for 10 mins followed by [3H]serotonin addition measured after 20 mins by liquid scintillation counting method
Inhibition of human SERT expressed in CHO cell membranes assessed as reduction in [3H]serotonin uptake preincubated for 10 mins followed by [3H]serotonin addition measured after 20 mins by liquid scintillation counting method
|
[PMID: 27865645] |
化学情報
-
CAS 番号 96847-55-1
-
性状 Liquid (Density: 1.077±0.06 g/cm3)
-
分子量 246.35
-
分子式 C15H22N2O
-
Color Colorless to light yellow
-
SMILES
O=C([C@@]1(C2=CC=CC=C2)[C@@H](CN)C1)N(CC)CC
-
別名
(1R,2S)-Milnacipran; F2696
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (202.96 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (274 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0593 mL | 20.2963 mL | 40.5927 mL | 101.4816 mL |
| 5 mM | 0.8119 mL | 4.0593 mL | 8.1185 mL | 20.2963 mL | |
| 10 mM | 0.4059 mL | 2.0296 mL | 4.0593 mL | 10.1482 mL | |
| 15 mM | 0.2706 mL | 1.3531 mL | 2.7062 mL | 6.7654 mL | |
| 20 mM | 0.2030 mL | 1.0148 mL | 2.0296 mL | 5.0741 mL | |
| 25 mM | 0.1624 mL | 0.8119 mL | 1.6237 mL | 4.0593 mL | |
| 30 mM | 0.1353 mL | 0.6765 mL | 1.3531 mL | 3.3827 mL | |
| 40 mM | 0.1015 mL | 0.5074 mL | 1.0148 mL | 2.5370 mL | |
| 50 mM | 0.0812 mL | 0.4059 mL | 0.8119 mL | 2.0296 mL | |
| 60 mM | 0.0677 mL | 0.3383 mL | 0.6765 mL | 1.6914 mL | |
| 80 mM | 0.0507 mL | 0.2537 mL | 0.5074 mL | 1.2685 mL | |
| 100 mM | 0.0406 mL | 0.2030 mL | 0.4059 mL | 1.0148 mL |
Dextromilnacipran 関連分類
HY-14794 関連分類
Powered by Bioz