Dihydroxyacetone phosphate
Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research.
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- CAS 番号: 57-04-5
- 分子式: C3H7O6P
- 分子量:170.06
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Human Endogenous Metabolite |
Dihydroxyacetone phosphate can be used in fructose metabolism, triose and glycation research[1].
Dihydroxyacetone phosphate has potential glycating effects to form advanced glycation end products (AGEs)[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 57-04-5
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性状 Oil
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分子量 170.06
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分子式 C3H7O6P
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Color Colorless to light yellow
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SMILES
O=C(COP(O)(O)=O)CO
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別名
DHAP
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (588.03 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Shimakawa G, et al. The Calvin cycle inevitably produces sugar-derived reactive carbonyl methylglyoxal during photosynthesis: a potential cause of plant diabetes. Plant Cell Physiol. 2014 Feb;55(2):333-40. [Content Brief]
[3]. Ahmad S, et al. Inhibitory effect of metformin and pyridoxamine in the formation of early, intermediate and advanced glycation end-products. PLoS One. 2013 Sep 4;8(9):e72128. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8803 mL | 29.4014 mL | 58.8028 mL | 147.0069 mL |
| 5 mM | 1.1761 mL | 5.8803 mL | 11.7606 mL | 29.4014 mL | |
| 10 mM | 0.5880 mL | 2.9401 mL | 5.8803 mL | 14.7007 mL | |
| 15 mM | 0.3920 mL | 1.9601 mL | 3.9202 mL | 9.8005 mL | |
| 20 mM | 0.2940 mL | 1.4701 mL | 2.9401 mL | 7.3503 mL | |
| 25 mM | 0.2352 mL | 1.1761 mL | 2.3521 mL | 5.8803 mL | |
| 30 mM | 0.1960 mL | 0.9800 mL | 1.9601 mL | 4.9002 mL | |
| 40 mM | 0.1470 mL | 0.7350 mL | 1.4701 mL | 3.6752 mL | |
| 50 mM | 0.1176 mL | 0.5880 mL | 1.1761 mL | 2.9401 mL | |
| 60 mM | 0.0980 mL | 0.4900 mL | 0.9800 mL | 2.4501 mL | |
| 80 mM | 0.0735 mL | 0.3675 mL | 0.7350 mL | 1.8376 mL | |
| 100 mM | 0.0588 mL | 0.2940 mL | 0.5880 mL | 1.4701 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.