Eicosanedioic acid
Based on 1 Customer Validation
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.0%
- CAS 番号: 2424-92-2
- 分子式: C20H38O4
- 分子量:342.51
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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Non-cleavable Linker |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 2424-92-2
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性状 Solid
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分子量 342.51
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分子式 C20H38O4
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Color White to off-white
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SMILES
O=C(O)CCCCCCCCCCCCCCCCCCC(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (72.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9196 mL | 14.5981 mL | 29.1962 mL | 72.9906 mL |
| 5 mM | 0.5839 mL | 2.9196 mL | 5.8392 mL | 14.5981 mL | |
| 10 mM | 0.2920 mL | 1.4598 mL | 2.9196 mL | 7.2991 mL | |
| 15 mM | 0.1946 mL | 0.9732 mL | 1.9464 mL | 4.8660 mL | |
| 20 mM | 0.1460 mL | 0.7299 mL | 1.4598 mL | 3.6495 mL | |
| 25 mM | 0.1168 mL | 0.5839 mL | 1.1678 mL | 2.9196 mL | |
| 30 mM | 0.0973 mL | 0.4866 mL | 0.9732 mL | 2.4330 mL | |
| 40 mM | 0.0730 mL | 0.3650 mL | 0.7299 mL | 1.8248 mL | |
| 50 mM | 0.0584 mL | 0.2920 mL | 0.5839 mL | 1.4598 mL | |
| 60 mM | 0.0487 mL | 0.2433 mL | 0.4866 mL | 1.2165 mL |
Eicosanedioic acid 関連分類
HY-W034595 関連分類
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