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Epcoritamab

(別名: GEN3013)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Epcoritamab (GEN3013) is an bispecific IgG1 antibody redirecting T-cells toward CD3×CD20+ tumor cells. Epcoritamab induces potent T-cell-mediated cytotoxicity towards B-cell NHL cell lines.

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  • 純度: 99.84%
  • CAS 番号: 2134641-34-0
  • 分子量:146.28 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Epcoritamab
  • Experimental Validation Results for Epcoritamab
  • Experimental Validation Results for Epcoritamab
  • Epcoritamab Chemical Structure
    Epcoritamab 構造式
CAS 番号: 2134641-34-0
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609-228-6898
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最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Ig(G1-kappa_G1-lambda2)

  • 1/16

    Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Epcoritamab. The EC50 for this effect is 2.85 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Epcoritamab (HY-P99931). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Epcoritamab Chemical Structure
    1/16
  • Epcoritamab
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Epcoritamab. The EC50 for this effect is 2.85 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Epcoritamab (HY-P99931). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Ig(G1-kappa_G1-lambda2)