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製品番号: HY-16740

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Eprociclovir

(別名: A-5021)

Eprociclovir is an antiviral drug with nucleoside analogues. The triphosphate form of Eprociclovir is converted into the active form within virus-infected cells by the virus and possible cellular enzymes, including the viral thymidine kinase, thereby inhibiting the activity of the viral DNA polymerase. The primary activity of Eprociclovir is against herpes viruses, including but not limited to cytomegalovirus (CMV) and herpes simplex virus (HSV). Eprociclovir can be used in studies interfered with by sensitive viruses.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 145512-85-2
分子式: C₁₁H₁₅N₅O₃
分子量:265.27

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Eprociclovir 構造式

CAS 番号: 145512-85-2

容量

価格（税別）

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数量

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target

DNA Polymerase

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	>100 μg/mL Compound: 3a	Inhibitory activity against 1RF strain of HIV-1 by plaque reduction assay in CEM cells Inhibitory activity against 1RF strain of HIV-1 by plaque reduction assay in CEM cells	[PMID: 9548818]
HEL	IC₅₀	0.67 μg/mL Compound: 1	Tested for inhibitory activity against Varicella zoster virus(VZV) by plaque reduction assay using HEL cells Tested for inhibitory activity against Varicella zoster virus(VZV) by plaque reduction assay using HEL cells	[PMID: 10649983]
HEL	IC₅₀	0.67 μg/mL Compound: 1	Tested for Antiherpetic activity against VZV from Kawaguchi strain in HEL cell lines. Tested for Antiherpetic activity against VZV from Kawaguchi strain in HEL cell lines.	[PMID: 10649983]
HFF	IC₅₀	0.2 μg/mL Compound: 3a	Inhibitory activity against DM625 strain of zoster virus(VZV) by plaque reduction assay in HFF cells Inhibitory activity against DM625 strain of zoster virus(VZV) by plaque reduction assay in HFF cells	[PMID: 9548818]
MRC5	IC₅₀	0.0093 μg/mL Compound: 1	Tested for Antiherpetic activity against HSV-1 from Tomioka strain in MRC-5 cell lines. Tested for Antiherpetic activity against HSV-1 from Tomioka strain in MRC-5 cell lines.	[PMID: 10649983]
MRC5	IC₅₀	0.12 μg/mL Compound: 1	Tested for Antiherpetic activity against HSV-2 from 186 strain in MRC-5 cell lines. Tested for Antiherpetic activity against HSV-2 from 186 strain in MRC-5 cell lines.	[PMID: 10649983]
MRC5	IC₅₀	0.21 μg/mL Compound: 1	Tested for Antiherpetic activity against VZV from clinical isolates of MRC-5 cell lines.(average of six isolates) Tested for Antiherpetic activity against VZV from clinical isolates of MRC-5 cell lines.(average of six isolates)	[PMID: 10649983]
Vero	CC₅₀	240 μg/mL Compound: 1	Tested for cytotoxicity in vero cells, activity is expressed as CC50. Tested for cytotoxicity in vero cells, activity is expressed as CC50.	[PMID: 10649983]
Vero	CC₅₀	240 μg/mL Compound: 3a	Cytotoxic concentration to uninfected vero cells Cytotoxic concentration to uninfected vero cells	[PMID: 9548818]
Vero	IC₅₀	0.02 μg/mL Compound: 3a	Inhibition of Tomioka strain of herpes simplex virus( Tomioka strain of HSV-1) by quantitative CPE reduction assay in vero cells Inhibition of Tomioka strain of herpes simplex virus( Tomioka strain of HSV-1) by quantitative CPE reduction assay in vero cells	[PMID: 9548818]

化学情報

CAS 番号 145512-85-2
分子量 265.27
分子式 C₁₁H₁₅N₅O₃
SMILES

OC[C@@]1([C@@H](C1)CO)CN2C3=C(C(N=C(N3)N)=O)N=C2
別名

A-5021
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Gandar F, et al. In vitro and in vivo assessment of eprociclovir as antiviral treatment against testudinid herpesvirus 3 in Hermann's tortoise (Testudo hermanni)[J]. Research in veterinary science, 2019, 124: 20-23. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

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Eprociclovir

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Eprociclovir 関連分類

HY-16740 関連分類