Eucatropine
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC50 value of 0.583 μM. Eucatropine acts as an anticholinergic agent. Eucatropine produces behavioral effects via central cholinergic receptive sites in cats.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 100-91-4
- 分子式: C17H25NO3
- 分子量:291.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male and female (2-4 kg; intracerebroventricular cannula implantation)[1]
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Dosage:0.2 mg, 0.5 mg, 1.0 mg, 2.0 mg
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Administration:i.c.v.; single injection
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Result:Produced inconsistent emotional effects including miaowing, loud calling, loss of interest of the surroundings, rage, threat, attack, defense, fighting with paws, and flight; no restlessness, impelling locomotion, vacant staring, or apprehension.
Caused consistent mydriasis and tachypnea; inconsistent dyspnea, licking, vomiting, salivation, defecation, and micturition.
Induced consistent ataxia; no scratching, rigidity, weakness with adynamia, myoclonic jerks, or convulsions.
Showed no measurable impelling locomotion at any tested dose.
Caused very short-duration, non-dose-dependent aggressive fighting behavior with mean duration near 0 minutes across all tested doses.
化学情報
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CAS 番号 100-91-4
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分子量 291.39
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分子式 C17H25NO3
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SMILES
O=C(OC1CC(C)(C)N(C)C(C)C1)C(O)C2=CC=CC=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Beleslin DB, et al. Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression. Pharmacol Biochem Behav. 1986;24(3):581-586. [Content Brief]
[2]. Schmeller T, et, al. Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptors. Pharmazie. 1995 Jul;50(7):493-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)