Fluc-IN-1
Based on 1 Customer Validation
Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.44%
- CAS 番号: 2940242-10-2
- 分子式: C26H23N3O2S2
- 分子量:473.61
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
IC50: 25 nM (firefly luciferase)
化学情報
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CAS 番号 2940242-10-2
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性状 Solid
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分子量 473.61
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分子式 C26H23N3O2S2
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Color White to off-white
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SMILES
O=C(C1=CC=C(C)C=C1C)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 116.67 mg/mL (246.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1114 mL | 10.5572 mL | 21.1144 mL | 52.7860 mL |
| 5 mM | 0.4223 mL | 2.1114 mL | 4.2229 mL | 10.5572 mL | |
| 10 mM | 0.2111 mL | 1.0557 mL | 2.1114 mL | 5.2786 mL | |
| 15 mM | 0.1408 mL | 0.7038 mL | 1.4076 mL | 3.5191 mL | |
| 20 mM | 0.1056 mL | 0.5279 mL | 1.0557 mL | 2.6393 mL | |
| 25 mM | 0.0845 mL | 0.4223 mL | 0.8446 mL | 2.1114 mL | |
| 30 mM | 0.0704 mL | 0.3519 mL | 0.7038 mL | 1.7595 mL | |
| 40 mM | 0.0528 mL | 0.2639 mL | 0.5279 mL | 1.3197 mL | |
| 50 mM | 0.0422 mL | 0.2111 mL | 0.4223 mL | 1.0557 mL | |
| 60 mM | 0.0352 mL | 0.1760 mL | 0.3519 mL | 0.8798 mL | |
| 80 mM | 0.0264 mL | 0.1320 mL | 0.2639 mL | 0.6598 mL | |
| 100 mM | 0.0211 mL | 0.1056 mL | 0.2111 mL | 0.5279 mL |