Gamhepathiopine
Gamhepathiopine is a thienopyrimidinone compound. Gamhepathiopine exerts antimalarial effects by targeting the Qo site of Plasmodium falciparum cytochrome b and inhibiting the activity of complex III in the electron transport chain.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1620442-30-9
- 分子式: C17H19N3OS
- 分子量:313.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | CC50 |
27.5 μM
Compound: 1
|
Cytotoxicity against CHO cells assessed as cell viability after 24 hrs by MTT assay
Cytotoxicity against CHO cells assessed as cell viability after 24 hrs by MTT assay
|
[PMID: 25791675] |
| Hepatocyte | CC50 |
>200 μM
Compound: 1
|
Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
|
[PMID: 36680984] |
| HepG2 | CC50 |
25.6 μM
Compound: 1
|
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 25791675] |
化学情報
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CAS 番号 1620442-30-9
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分子量 313.42
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分子式 C17H19N3OS
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SMILES
CC1=CC=C(C2=CC(N=C(NC(C)(C)C)NC3=O)=C3S2)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)