Ganoderic acid B
Based on 1 Customer Validation
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.60%
- CAS 番号: 81907-61-1
- 分子式: C30H44O7
- 分子量:516.67
-
保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Immunology/Inflammation Compound Library
HY-L007
-
Metabolism/Protease Compound Library
HY-L012
-
Natural Product Library
HY-L021
-
Antiviral Compound Library
HY-L027
-
Lipid Compound Library
HY-L043
-
Medicine Food Homology Compound Library
HY-L055
-
Terpenoids Library
HY-L056
-
Pyroptosis Compound Library
HY-L059
-
Traditional Chinese Medicine Active Compound Library
HY-L065
-
Food-Sourced Compound Library
HY-L094
-
Antiviral Traditional Chinese Medicine Active Compound Library
HY-L113
-
Anti-inflammatory Traditional Chinese Medicine Active Compound Library
HY-L114
-
Plant-Sourced Natural Product Library
HY-L115
-
Human Metabolite Library
HY-L123
-
Protease Inhibitor Library
HY-L147
-
Multi-Target Compound Library
HY-L176
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Natural Product Library Plus
HY-L021P
-
Natural Product and Natural Product-Like Compound Library
HY-L021M
-
Bioactive Compound Library
HY-L001
-
Fatty Acids Compound Library
HY-L182
-
Miao Ethnicity Medicine Compound Library
HY-L190
-
High-Throughput Bioactive Compound Library
HY-L205
-
High-Throughput Natural Product Library
HY-L206
-
Mass Spectrometry Human Metabolite Library
HY-L215
-
Diarrhea-Related Traditional Chinese Medicine Active Compound Library
HY-L224
-
Natural Product Diversity Scaffold Library
HY-L245
-
Mass Spectrometry Natural Product Library
HY-L262
生物活性
HIV-1 protease[3]
Ganoderic acid B (5 mg/kg, s.c.) shows antinociceptive effects in acetic acid-induced writhing in mice[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:LPS-induced pneumonia mice[4]
-
Dosage:3 or 6 mg/kg
-
Administration:i.p.
-
Result:Reduced Lung dry/wet weight (W/D) and myeloperoxidase activity in lung.
Increased SOD, decreased MDA, TNF-α, IL-1β and IL-6 level.
化学情報
-
CAS 番号 81907-61-1
-
性状 Solid
-
分子量 516.67
-
分子式 C30H44O7
-
Color White to light brown
-
SMILES
C[C@]([C@@]([C@]([C@H](C)CC(C[C@@H](C)C(O)=O)=O)([H])C1)(CC2=O)C)(C1=O)C([C@H](C[C@@]3([H])C4(C)C)O)=C2[C@]3(CC[C@@H]4O)C
-
別名
ガノデル酸B
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 50 mg/mL (96.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (275 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Zhou S, et al. Triterpenes and Soluble Polysaccharide Changes in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), During Fruiting Growth. Int J Med Mushrooms. 2018;20(9):859-871. [Content Brief]
[2]. Zheng DS, et al. Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Exp Ther Med. 2017 Oct;14(4):3273-3278. [Content Brief]
[3]. el-Mekkawy S, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49(6):1651-7. [Content Brief]
[4]. Shi J, et al. Ganoderic acid B attenuates LPS-induced lung injury. Int Immunopharmacol. 2020 Nov;88:106990. [Content Brief]
[5]. Koyama K, et al. Antinociceptive components of Ganoderma lucidum. Planta Med. 1997 Jun;63(3):224-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9355 mL | 9.6774 mL | 19.3547 mL | 48.3868 mL |
| 5 mM | 0.3871 mL | 1.9355 mL | 3.8709 mL | 9.6774 mL | |
| 10 mM | 0.1935 mL | 0.9677 mL | 1.9355 mL | 4.8387 mL | |
| 15 mM | 0.1290 mL | 0.6452 mL | 1.2903 mL | 3.2258 mL | |
| 20 mM | 0.0968 mL | 0.4839 mL | 0.9677 mL | 2.4193 mL | |
| 25 mM | 0.0774 mL | 0.3871 mL | 0.7742 mL | 1.9355 mL | |
| 30 mM | 0.0645 mL | 0.3226 mL | 0.6452 mL | 1.6129 mL | |
| 40 mM | 0.0484 mL | 0.2419 mL | 0.4839 mL | 1.2097 mL | |
| 50 mM | 0.0387 mL | 0.1935 mL | 0.3871 mL | 0.9677 mL | |
| 60 mM | 0.0323 mL | 0.1613 mL | 0.3226 mL | 0.8064 mL | |
| 80 mM | 0.0242 mL | 0.1210 mL | 0.2419 mL | 0.6048 mL |
Ganoderic acid B 関連分類
HY-N2006 関連分類
Powered by Bioz