Cd33 - CD33 molecule Gene

Also Known as gp67; Siglec-3

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 12489

Summary

Predicted to enable protein Phosphatase binding activity and sialic acid binding activity. Predicted to be involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine Phosphatase activity. Predicted to be located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. Predicted to be active in plasma membrane. Is expressed in central nervous system; genitourinary system; spleen; and submandibular gland. Orthologous to human CD33 (CD33 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd33 Products (2)

mRNA Protein Name
NM_001111058.1 NP_001104528.1 myeloid cell surface antigen CD33 isoform 1 precursor
NM_021293.3 NP_067268.1 myeloid cell surface antigen CD33 isoform 2 precursor
Protein Preferred Names Protein Names

myeloid cell surface antigen CD33

  • CD33 antigen

  • sialic acid-binding Ig-like lectin 3

Recombinant Cd33 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P72473 Siglec-3/CD33 Protein, Mouse (HEK293, His) Q63994-1 (D18-E240) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73640 Siglec-3/CD33 Protein, Mouse (HEK293, Fc) Q63994-1 (Q17-E240) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P73641 Siglec-3/CD33 Protein, Mouse (HEK293) Q63994-1 (Q17-E240) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Rare Diseases
HY-109539 Gemtuzumab ozogamicin Inducer 98.00% Unkown

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-171792 BMS-986497 Inhibitor / Phase 1
阻害性抗体 (6)
製品番号 製品名 製品効果
純度 Phase
HY-P99971 Gemtuzumab 99.54% Phase 4
HY-P99329 Vadastuximab 99.23% Phase 3
HY-P9983 Lintuzumab Inhibitor 98.09% Phase 3
HY-P99910 Eluvixtamab Ligand 97.28% Phase 1
HY-P99958 Vixtimotamab Inhibitor 97.29% Phase 1
HY-P991364 Aldastotug Inhibitor 99.9% Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-144399 CD33 splicing modulator 1 Inhibitor 99.05% Unkown
HY-160649 MC-Gly-Gly-Phe-Gly-GABA-Exatecan Inhibitor 99.72% Unkown
HY-109539A Gemtuzumab ozogamicin (solution) Inducer / Unkown
HY-144399A CD33 splicing modulator 1 hydrochloride Modulator / Unkown
HY-RS02235 CD33 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17093 Cd33 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23537 Cd33 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
阻害性抗体 (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-P990903 Avitotamig Inhibitor 95.98% Unkown
HY-P991365 DS-1501 Inhibitor / Unkown
HY-P990505 Anti-Siglec-15/CD33L3 Antibody Inhibitor 98.6674% Unkown
HY-P991517 BI-836858 95.81% Unkown
HY-P9S0124 Anti-CD33 Antibody (OR000283) 99.00% Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Cd33 NCBI NCBI:945