HPN601
HPN601 is a monoclonal antibody targeting CD326/EPCAM, as well as a protease-activated EpCAM-targeted T cell engager. HPN601 binds to EPCAM, CD3e and albumin, and induces T cell-mediated tumor cell killing. HPN601 significantly reduces the release levels of IFN-γ, IL-2, IL-6, and IL-10. HPN601 can be used for relevant research on cancers such as breast cancer and gastric cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Human
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IL-2 |
IL-6 |
IL-10 |
HPN601 demonstrates a tenfold improved therapeutic window compared to a constitutively active EpCAM-targeting T cell engager and significantly attenuates cytokine production including IFN-γ, IL-2, IL-6, and IL-10 in non-human primates[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
EpCAM/TROP1/CD326
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
化学情報
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HPN601 関連分類
HY-P992370 関連分類
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