Hydroxylamine (50% w/w in water)
Based on 2 publication(s) in Google Scholar
Hydroxylamine (50% w/w in water) is an inorganic highly reactive compound and antibacterial agent. Hydroxylamine (50% w/w in water) acutely activates the transport activity of GLUT1, inhibits Monoamine oxidase activity. Hydroxylamine (50% w/w in water) inhibits nitrite oxidizing bacteria. Hydroxylamine (50% w/w in water) activates glucose uptake. Hydroxylamine (50% w/w in water) can be used in the research of inflammatory diseases and allergies[1][2][3][4].
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 7803-49-8
- 分子式: H3NO
- 分子量:33.03
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保管条件:
Solution, -20°C, 2 years
MedChemExpress(MCE)の使用を引用している文献 Hydroxylamine (50% w/w in water)
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生物活性
製品説明
IC50 & Target
[1]|
GLUT1 |
体外実験
Hydroxylamine (1.0-20.0 mM; 0-20 min) acutely activates glucose uptake in L929 fibroblast cells in a dose-dependent manner[1].
Hydroxylamine (5.0 mM) has its glucose uptake activation in L929 fibroblast cells blocked by pretreatment with Iodoacetamide[1].
Hydroxylamine (1 mM; 1 h) potently inhibits purified monoamine oxidase from Escherichia coli K-12 with 99.8% inhibition[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 7803-49-8
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性状 Liquid
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分子量 33.03
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分子式 H3NO
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Color Colorless to light yellow
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SMILES
ON
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
Publications (2)
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Journal Impact Factor
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Most Recent
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Research (Wash D C)
EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation. [Abstract]2025 Nov 25:8:1001. PMID: 41306774 -
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
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データシート (270 KB)
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SDS (926 KB)
- English - EN (926 KB)
- Français - FR (926 KB)
- Deutsch - DE (926 KB)
- Norwegian - NO (926 KB)
- Español - ES (926 KB)
- Swedish - SV (926 KB)
- Italian - IT (926 KB)
- Korean - KR (926 KB)
- Portuguese - PT (926 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Kataoka H, et al. Anti-inflammatory and anti-allergic activities of hydroxylamine and related compounds. Biol Pharm Bull. 2002 Nov;25(11):1436-41. [Content Brief]
[2]. Zhang R, et al. Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress. Free Radic Biol Med. 1998 Jan 1;24(1):66-75. [Content Brief]
[3]. Soler-Jofra A, et al. Hydroxylamine and the nitrogen cycle: A review. Water Res. 2021 Feb 15;190:116723. [Content Brief]
[4]. Louters LL, et al. Hydroxylamine acutely activates glucose uptake in L929 fibroblast cells. Biochimie. 2013;95(4):787-792. [Content Brief]
[5]. Roh JH, et al. Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12. Biosci Biotechnol Biochem. 1994;58(9):1652-1656. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)