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United States

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製品番号: HY-206897

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Insecticidal agent 34

Insecticidal agent 34 is an orally active insecticide. Insecticidal agent 34 inhibits voltage-gated sodium channel and blocks acetylcholine release. Insecticidal agent 34 induces ataxia, paralysis, curling, tremors/convulsions and progressive death in lepidopteran larvae, inhibits neural activity in the central nervous system, and blocks nerve firing in larval stretch receptor preparations. Insecticidal agent 34 can be used for insecticidal research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 183992-66-7
分子式: C₂₉H₂₈F₆N₂O₅
分子量:598.53

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 34 構造式

CAS 番号: 183992-66-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Sodium Channel アイソフォーム固有の製品をすべて表示 :

体外実験

Insecticidal agent 34 (Compound 4) potently inhibits veratridine-induced acetylcholine release from synaptosomes of the house cricket (Acheta domesticus), with a pIC₅₀ of 6.56^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

体内実験

Insecticidal agent 34 (feed mixing; continuous administration; 10 days) exhibits delayed in vivo toxicity against late 2nd-instar Heliothis virescens larvae. After 10 days of feed exposure, its lethal pLC₅₀ is 5.7 and growth-inhibitory pI₅₀ is 6.56^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

late second instar larvae^[1]
Dosage:

Diet incorporation
Administration:

continuous; 10 days
Result:

Exhibited slow-onset toxicity with an LC₅₀ corresponding to a pLC₅₀ of 5.7 after 10 days of diet exposure.
Achieved an IC₅₀ for growth inhibition corresponding to a pI₅₀ of 6.56 after 10 days of diet exposure.

化学情報

CAS 番号 183992-66-7
分子量 598.53
分子式 C₂₉H₂₈F₆N₂O₅
SMILES

O=C(NC1=CC=C(CN2CCC(C(C3=CC=C(C=C3)OC(F)(F)F)(C4=CC=C(C=C4)OC(F)(F)F)O)CC2)C=C1)OC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. J.R Bloomquist, et al. Toxicity and mode of action of benzhydrolpiperidines and related compounds in insects. Pesticide Biochemistry and Physiology
Volume 73, Issue 1, May 2002, Pages 18-26.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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