IST-622
IST-622 (6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin) is an anti-tumor agent with significant growth inhibitory activity. IST-622 exhibits significant anti-tumor effects against a variety of mouse tumors such as P388 and L1210 leukemias, B16 melanoma, Lewis lung carcinoma, Colon 26 and Colon 38 adenocarcinomas, and M5076 reticulum cell sarcoma. IST-622 was orally administered and the results showed efficacy in different tumor types. In addition, IST-622 provided significant inhibitory effects against two human tumor xenograft models: large cell lung carcinoma (Lu-116) and gastric adenocarcinoma (St-4). IST-622 also exhibited significant growth inhibitory activity against P388 leukemia in vitro, with a half inhibitory concentration (IC50) more than 20 times lower than CT.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 128201-92-3
- 分子式: C44H44O16
- 分子量:828.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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CAS 番号 128201-92-3
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分子量 828.81
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分子式 C44H44O16
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SMILES
CCOCCC(OC1=C(C=CC=C2O[C@H]3[C@@H]([C@]4([H])[C@](O[C@H](C5=CC=CC=C5)O4)([H])[C@H](O3)C)O[C@@H]6[C@@H]([C@H]([C@H]([C@H](O6)C)O)OC)O)C2=C(OC(C7=C(C)C=CC(O8)=C79)=O)C9=C1C8=O)=O
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別名
6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)