Ixazomib-d7
Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2177240-89-8
- 分子式: C14H12D7BCl2N2O4
- 分子量:368.07
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 2177240-89-8
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非標識Cas 1072833-77-2
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分子量 368.07
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分子式 C14H12D7BCl2N2O4
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C[C@@H](B(O)O)NC(CNC(C1=C(C=CC(Cl)=C1)Cl)=O)=O
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別名
MLN2238-d7
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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