L-649923
L-649923 is an orally active CysLT1 antagonist. L-649923 reduced the incidence of gastritis in an animal model of acute gastric mucosal injury. L-649923 can be used in research on diseases such as asthma and gastritis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 114370-57-9
- 分子式: C25H32O6S
- 分子量:460.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Leukotriene Receptor アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 114370-57-9
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分子量 460.58
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分子式 C25H32O6S
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SMILES
OC(C[C@H](C)[C@@H](O)C(C=C1)=CC=C1SCCCOC2=C(C(O)=C(C(C)=O)C=C2)CCC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Gyömber E, et al. Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat. J Gastroenterol Hepatol. 1996 Oct;11(10):922-7. [Content Brief]
[2]. Jacques CA, et al. The contractile activities of lipoxin A4 and lipoxin B4 for guinea-pig airway tissues. Br J Pharmacol. 1988 Oct;95(2):562-8. [Content Brief]
[3]. McMahon TJ, et al. Influence of SQ 30741 on thromboxane receptor-mediated responses in the feline pulmonary vascular bed. J Appl Physiol (1985). 1991 Nov;71(5):2012-8. [Content Brief]
[4]. Küng CF, et al. Different mechanisms of endothelial dysfunction with aging and hypertension in rat aorta. Hypertension. 1995 Feb;25(2):194-200. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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