Lytx-Pa2a
Lytx-Pa2a (Lycotoxin-Pa2a) is a peptide inhibitor against bacterial membranes and TLR4 receptor. Lytx-Pa2a exerts antimicrobial effects via non-competitive disruption of outer/cytoplasmic membranes and suppression of LPS-induced TLR4/NF-κB signaling. Lytx-Pa2a is promising for research of bacterial infection and inflammation-related disease (e.g., sepsis).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C314H494N94O91S8
- 分子量:7298.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
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TLR4 |
化学情報
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分子量 7298.38
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分子式 C314H494N94O91S8
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別名
Lycotoxin-Pa2a; TBIU041425
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配列
Lys-Glu-Cys-Ile-Pro-Lys-His-His-Glu-Cys-Thr-Ser-Asn-Lys-Lys-Gly-Cys-Cys-Arg-Gly-Lys-Leu-Phe-Lys-Tyr-Lys-Cys-Gln-Cys-Thr-Thr-Val-Val-Asp-Gln-Ser-Gly-Glu-Gln-Ala-Glu-Arg-Cys-Phe-Cys-Gly-Thr-Ala-Thr-His-His-Lys-Ala-Ala-Glu-Leu-Val-Val-Gly-Phe-Gly-Lys-Lys-Leu-Phe-Gly (disulfide bridge:Cys3-Cys18,Cys10-Cys27,Cys17-Cys45,Cys29-Cys43)
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シーケンスの短縮
KECIPKHHECTSNKKGCCRGKLFKYKCQCTTVVDQSGEQAERCFCGTATHHKAAELVVGFGKKLFG (disulfide bridge:Cys3-Cys18,Cys10-Cys27,Cys17-Cys45,Cys29-Cys43)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)