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製品番号: HY-151940

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Mal-Pc

Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells.

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CAS 番号: 2670367-74-3
分子式: C₄₆H₂₈N₁₀O₈Si
分子量:876.86

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (280 KB)

Mal-Pc 構造式

CAS 番号: 2670367-74-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Having two maleimide axial substituents, Mal-Pc exhibits faster accumulation in cancer cells and then can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS-mediated anticancer effect of PDT^[1].
The fluorescence imaging demonstrated that Mal-Pc eliminate from normal cells faster due to the highly hydrophilic reaction product^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2670367-74-3
分子量 876.86
分子式 C₄₆H₂₈N₁₀O₈Si
SMILES

O=C(N1CCC(O[Si]234(OC(CCN5C(C=CC5=O)=O)=O)N6C(C7=C(C6=NC(C8=C9C=CC=C8)=[N]4C9=N%10)C=CC=C7)=NC(C%11=C%12C=CC=C%11)=[N]2C%12=NC%13=C(C=CC=C%14)C%14=C%10N%133)=O)C=CC1=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (280 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Juanjuan Chen, et al. Novel molecular photosensitizer with simultaneously GSH depletion, aggregation inhibition and accelerated elimination for improved and safe photodynamic therapy. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114938. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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