MitoTEMPOL
Based on 4 publication(s) in Google Scholar
MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.9%
- CAS 番号: 1101113-39-6
- 分子式: C32H42BrNO2P*
- 分子量:583.56
-
保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
MedChemExpress(MCE)の使用を引用している文献 MitoTEMPOL
More
生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
-
CAS 番号 1101113-39-6
-
性状 Solid
-
分子量 583.56
-
分子式 C32H42BrNO2P*
-
Color Brown to orange
-
SMILES
[O]N1C(C)(CC(CC1(C)C)OCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (4)
-
Journal Impact Factor
-
Most Recent
-
Redox Biol
Advanced glycation end-products exacerbate myocardial ischemia/reperfusion injury by promoting mitochondrial oxidative damage and PANoptosis in diabetes mellitus. [Abstract]2026 Jul:94:104228. PMID: 42176503 -
Cell Rep Med
Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis. [Abstract]2025 Sep 25:102371. PMID: 41005298 -
Int J Dent
The ROS/CaMK II/β-Catenin Signaling Axis Affects the Osteogenic Potential of BMSCs and Disrupts Implant Osseointegration: An In Vitro Study. [Abstract]2025 Aug 15:2025:5566776. PMID: 40861924 -
bioRxiv
2025 Nov 13:2025.11.11.687895. PMID: 41292779
溶剤 & 溶解度
DMF : 50 mg/mL (85.68 mM; Need ultrasonic and warming)
Ethanol : 50 mg/mL (85.68 mM; Need ultrasonic and warming)
DMSO : 50 mg/mL (85.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / Ethanol / DMSO | 1 mM | 1.7136 mL | 8.5681 mL | 17.1362 mL | 42.8405 mL |
| 5 mM | 0.3427 mL | 1.7136 mL | 3.4272 mL | 8.5681 mL | |
| 10 mM | 0.1714 mL | 0.8568 mL | 1.7136 mL | 4.2840 mL | |
| 15 mM | 0.1142 mL | 0.5712 mL | 1.1424 mL | 2.8560 mL | |
| 20 mM | 0.0857 mL | 0.4284 mL | 0.8568 mL | 2.1420 mL | |
| 25 mM | 0.0685 mL | 0.3427 mL | 0.6854 mL | 1.7136 mL | |
| 30 mM | 0.0571 mL | 0.2856 mL | 0.5712 mL | 1.4280 mL | |
| 40 mM | 0.0428 mL | 0.2142 mL | 0.4284 mL | 1.0710 mL | |
| 50 mM | 0.0343 mL | 0.1714 mL | 0.3427 mL | 0.8568 mL | |
| 60 mM | 0.0286 mL | 0.1428 mL | 0.2856 mL | 0.7140 mL | |
| 80 mM | 0.0214 mL | 0.1071 mL | 0.2142 mL | 0.5355 mL |