MM-206
Based on 1 Customer Validation
MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.9%
- CAS 番号: 1809581-87-0
- 分子式: C22H12F5NO3S2
- 分子量:497.46
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
化学情報
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CAS 番号 1809581-87-0
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性状 Solid
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分子量 497.46
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分子式 C22H12F5NO3S2
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Color Off-white to light yellow
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SMILES
O=S(C1=C(C(F)=C(C(F)=C1F)F)F)(NC2=C3C=CC=CC3=C(C(SC4=CC=CC=C4)=C2)O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMF : 25 mg/mL (50.26 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.0102 mL | 10.0511 mL | 20.1021 mL | 50.2553 mL |
| 5 mM | 0.4020 mL | 2.0102 mL | 4.0204 mL | 10.0511 mL | |
| 10 mM | 0.2010 mL | 1.0051 mL | 2.0102 mL | 5.0255 mL | |
| 15 mM | 0.1340 mL | 0.6701 mL | 1.3401 mL | 3.3504 mL | |
| 20 mM | 0.1005 mL | 0.5026 mL | 1.0051 mL | 2.5128 mL | |
| 25 mM | 0.0804 mL | 0.4020 mL | 0.8041 mL | 2.0102 mL | |
| 30 mM | 0.0670 mL | 0.3350 mL | 0.6701 mL | 1.6752 mL | |
| 40 mM | 0.0503 mL | 0.2513 mL | 0.5026 mL | 1.2564 mL | |
| 50 mM | 0.0402 mL | 0.2010 mL | 0.4020 mL | 1.0051 mL |