NCI-B16
Based on 1 Customer Validation
NCI-B16 is a small molecule RNA binder obtained through RNA-small molecule interaction screening. NCI-B16 interacts with RNA motifs under competitive conditions. NCI-B16 is used for RNA-small molecule interaction studies.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.25%
- CAS 番号: 802835-01-4
- 分子式: C27H26N8O4
- 分子量:526.55
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
NCI-B16 remains among 91 unique RNA-binding small molecules after competitive screening with a 1,000-fold excess of bulk tRNA to exclude non-selective RNA motif binders[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 802835-01-4
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性状 Solid
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分子量 526.55
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分子式 C27H26N8O4
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Color White to off-white
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SMILES
O=C(C1=CC(NC(NC2=CC=C(C3=NCCN3)C=C2)=O)=CC(NC(NC4=CC=C(C5=NCCN5)C=C4)=O)=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (189.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8992 mL | 9.4958 mL | 18.9915 mL | 47.4789 mL |
| 5 mM | 0.3798 mL | 1.8992 mL | 3.7983 mL | 9.4958 mL | |
| 10 mM | 0.1899 mL | 0.9496 mL | 1.8992 mL | 4.7479 mL | |
| 15 mM | 0.1266 mL | 0.6331 mL | 1.2661 mL | 3.1653 mL | |
| 20 mM | 0.0950 mL | 0.4748 mL | 0.9496 mL | 2.3739 mL | |
| 25 mM | 0.0760 mL | 0.3798 mL | 0.7597 mL | 1.8992 mL | |
| 30 mM | 0.0633 mL | 0.3165 mL | 0.6331 mL | 1.5826 mL | |
| 40 mM | 0.0475 mL | 0.2374 mL | 0.4748 mL | 1.1870 mL | |
| 50 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9496 mL | |
| 60 mM | 0.0317 mL | 0.1583 mL | 0.3165 mL | 0.7913 mL | |
| 80 mM | 0.0237 mL | 0.1187 mL | 0.2374 mL | 0.5935 mL | |
| 100 mM | 0.0190 mL | 0.0950 mL | 0.1899 mL | 0.4748 mL |
NCI-B16 関連分類
HY-156215 関連分類
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Keywords
- NCI-B16
- 802835-01-4
- DNA/RNA Synthesis
- HCV RNA stem-loop SL I
- antisense oligonucleotide
- HCV RNA stem-loop SL II
- SGR-Neo-RLuc-JFH1-2A replicon cells
- subgenomic replicon cells
- HCV 3' UTR stem-loop II RNA motif
- hepatitis C virus
- RNase H-mediated cleavage
- HCV 3' UTR stem-loop I RNA motif
- HCV RNA replication
- Inhibitor
- inhibitor
- inhibit