Nidulalin A
Nidulalin A is a DNA topoisomerase II inhibitor with an IC50 of 2.2 μM. Nidulalin A has an IC50 of 172 μM for DNA topoisomerase I. Nidulalin A has certain cytotoxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 162901-86-2
- 分子式: C16H14O6
- 分子量:302.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Topoisomerase アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
0.14 μM
Compound: 1 (Nidulalin A)
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In vitro cytotoxic activity against human cancer cell line HCT116 by using MTT assay
In vitro cytotoxic activity against human cancer cell line HCT116 by using MTT assay
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[PMID: 10509910] |
| K562 | IC50 |
0.32 μM
Compound: 1 (Nidulalin A)
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In vitro cytotoxic activity against human cancer cell line K562 by using MTT assay
In vitro cytotoxic activity against human cancer cell line K562 by using MTT assay
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[PMID: 10509910] |
| P388 | IC50 |
0.024 μM
Compound: 1 (Nidulalin A)
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In vitro cytotoxic activity against murine cancer cell line P388 by using MTT assay
In vitro cytotoxic activity against murine cancer cell line P388 by using MTT assay
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[PMID: 10509910] |
化学情報
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CAS 番号 162901-86-2
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分子量 302.28
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分子式 C16H14O6
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SMILES
COC([C@]12C(C(C3=C(O)C=C(C)C=C3O2)=O)=CC=C[C@H]1O)=O
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Structure Classification
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Initial Source
Penicillium sp. AJ117292
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Nidulalin A 関連分類
HY-N4329 関連分類
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