NNRT-IN-9
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase (NNRT) inhibitor. NNRT-IN-9 has potent antiviral and anti-resistance activity against wild-type (WT) HIV-1 and various clinically relevant mutations (E138K and K103N + Y181C) with EC50s of 55, 67 and 3910 nM, respectively. NNRT-IN-9 can be used for acquired immune deficiency syndrome (AIDS) research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C22H16N6O
- 分子量:380.40
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
|
HIV-1 (WT) 55 nM (EC50) |
HIV-1 (E138K) 67 nM (EC50) |
HIV-1 (K103N+Y181C) 3910 nM (EC50) |
化学情報
-
分子量 380.40
-
分子式 C22H16N6O
-
SMILES
N#CC1=CC(N2C(N(CC3=CC=CC=C32)CC4=NNC5=NC=CC=C45)=O)=CC=C1
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)