Pexopiprant
Based on 1 Customer Validation
Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki < 100nM. Pexopiprant can be used in studies of asthma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.40%
- CAS 番号: 932708-14-0
- 分子式: C21H17Cl2F2NO4
- 分子量:456.27
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
IC50 & Target
[1]|
DP2 <100 nM (Ki) |
化学情報
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CAS 番号 932708-14-0
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性状 Solid
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分子量 456.27
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分子式 C21H17Cl2F2NO4
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Color Off-white to light yellow
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SMILES
O=C(O)COC1=C2C(OC(F)F)=C(CC3=CC=C(Cl)C=C3)C(CC)=NC2=C(Cl)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (219.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1917 mL | 10.9584 mL | 21.9168 mL | 54.7921 mL |
| 5 mM | 0.4383 mL | 2.1917 mL | 4.3834 mL | 10.9584 mL | |
| 10 mM | 0.2192 mL | 1.0958 mL | 2.1917 mL | 5.4792 mL | |
| 15 mM | 0.1461 mL | 0.7306 mL | 1.4611 mL | 3.6528 mL | |
| 20 mM | 0.1096 mL | 0.5479 mL | 1.0958 mL | 2.7396 mL | |
| 25 mM | 0.0877 mL | 0.4383 mL | 0.8767 mL | 2.1917 mL | |
| 30 mM | 0.0731 mL | 0.3653 mL | 0.7306 mL | 1.8264 mL | |
| 40 mM | 0.0548 mL | 0.2740 mL | 0.5479 mL | 1.3698 mL | |
| 50 mM | 0.0438 mL | 0.2192 mL | 0.4383 mL | 1.0958 mL | |
| 60 mM | 0.0365 mL | 0.1826 mL | 0.3653 mL | 0.9132 mL | |
| 80 mM | 0.0274 mL | 0.1370 mL | 0.2740 mL | 0.6849 mL | |
| 100 mM | 0.0219 mL | 0.1096 mL | 0.2192 mL | 0.5479 mL |