PF-1163A
PF-1163A is an antifungal agent that inhibits Ergosterol (HY-N0181) synthesis (IC50 = 12 ng/mL), which is found in a fermentation broth of Penicillium sp. PF-1163A also inhibits C-4 sterol methyl oxidase with an MIC value of 12.5 µg/mL.
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- CAS 番号: 258871-59-9
- 分子式: C27H43NO6
- 分子量:477.63
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 258871-59-9
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分子量 477.63
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分子式 C27H43NO6
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SMILES
O=C(O[C@@H](CC[C@@H](CCCCC(N1C)=O)C)C[C@@H](O)CCC)[C@@H]1CC2=CC=C(C=C2)OCCO
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Nose H, et al. PF1163A, a novel antifungal agent, inhibit ergosterol biosynthesis at C-4 sterol methyl oxidase. J Antibiot (Tokyo). 2002 Nov;55(11):969-74. [Content Brief]
[2]. Okabe M, et al. Macrolides from a Marine-Derived Fungus, Penicillium meleagrinum var. viridiflavum, Showing Synergistic Effects with Fluconazole against Azole-Resistant Candida albicans. J Nat Prod. 2016 Apr 22;79(4):1208-12. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
PF-1163A 関連分類
HY-123457 関連分類
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