Piroctone
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 50650-76-5
- 分子式: C14H23NO2
- 分子量:237.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
化学情報
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CAS 番号 50650-76-5
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分子量 237.34
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分子式 C14H23NO2
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SMILES
O=C1C=C(C)C=C(CC(CC(C)(C)C)C)N1O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Sigle HC, et al. In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans. Mycoses. 2006 May;49(3):159-68. [Content Brief]
[2]. Sidarovich V, et al. Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells. Mol Pharmacol. 2015;87(3):513-24. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)