Pithecolobine
Pithecolobine is a saponin-like alkaloid found in the bark, seeds, and leaves of Samanea saman. Pithecolobine can inhibit the growth of Gram-positive bacteria, Gram-negative bacteria, and pathogenic yeasts. Pithecolobine scavenges DPPH radicals. Pithecolobine can be used for the research of infections caused by pathogenic bacteria and yeasts.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 22368-82-7
- 分子式: C22H46N4O2
- 分子量:398.63
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Pithecolobine (0.25 mg/disc) exhibits concentration-dependent antimicrobial activity against Escherichia coli NCIM 2065, Klebsiella pneumoniae NCIM 2957, Proteus vulgaris NCIM 2027, Pseudomonas aeruginosa NCIM 5031, Salmonella typhi NCIM 2051, Staphylococcus aureus NCIM 2079, Streptococcus faecalis NCIM 5025, Candida albicans NCIM 3471, and Cryptococcus neoformans NCIM 3541[2].
Pithecolobine (0.95-1000 μg/mL; 24-48 h) inhibits and kills Escherichia coli NCIM 2065, Klebsiella pneumoniae NCIM 2957, Proteus vulgaris NCIM 2027, Pseudomonas aeruginosa NCIM 5031, Salmonella typhi NCIM 2051, Staphylococcus aureus NCIM 2079, Streptococcus faecalis NCIM 5025, Candida albicans NCIM 3471, and Cryptococcus neoformans NCIM 3541[2].
Pithecolobine (31-1000 μg/mL; 30 min) scavenges DPPH radicals with an IC50 of 250 μg/mL in a cell-free in vitro assay[2].
Pithecolobine (1000 μg/mL; 2 h) inhibits β-Carotene (HY-N0411)/Linoleic acid (HY-N0729) bleaching by 70.4% at a concentration of 1000 μg/mL in a cell-free in vitro assay[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 22368-82-7
-
分子量 398.63
-
分子式 C22H46N4O2
-
SMILES
O=C1NCCCN(CCCCNCCCNC(CCCCCCC)CCC1)O
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Pithecolobine
- 22368-82-7
- Bacterial
- Fungal
- Reactive Oxygen Species (ROS)
- Samanea saman
- DPPH radicals
- Escherichia coli NCIM 2065
- Gram-negative bacteria
- Staphylococcus aureus NCIM 2079
- human pathogenic bacteria
- Gram-positive bacteria
- Klebsiella pneumoniae NCIM 2957
- Candida albicans NCIM 3471
- human pathogenic yeasts
- Inhibitor
- inhibitor
- inhibit