(R)-D2PM
Based on 1 Customer Validation
(R)-D2PM is a dopamine transporter inhibitor. (R)-D2PM is an isomer of D2PM. (R)-D2PM increases dopamine concentration in the synaptic cleft by inhibiting dopamine reuptake, producing central sympathomimetic effects. (R)-D2PM can be used in studies of acute D2PM toxicity and cardiovascular toxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.93%
- CAS 番号: 22348-32-9
- 分子式: C17H19NO
- 分子量:253.34
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
製品説明
体外実験
(R)-D2PM binds the dopamine re-uptake transporter with Kibinding 0.04 μM and inhibits dopamine re-uptake with Kiuptake 0.17 μM, yielding a Kibinding:Kiuptake ratio of 4.25[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 22348-32-9
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性状 Solid
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分子量 253.34
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分子式 C17H19NO
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Color White to off-white
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SMILES
OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@@H]3NCCC3
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別名
(R)-Diphenylprolinol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 10 mg/mL (39.47 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (280 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9473 mL | 19.7363 mL | 39.4726 mL | 98.6816 mL |
| 5 mM | 0.7895 mL | 3.9473 mL | 7.8945 mL | 19.7363 mL | |
| 10 mM | 0.3947 mL | 1.9736 mL | 3.9473 mL | 9.8682 mL | |
| 15 mM | 0.2632 mL | 1.3158 mL | 2.6315 mL | 6.5788 mL | |
| 20 mM | 0.1974 mL | 0.9868 mL | 1.9736 mL | 4.9341 mL | |
| 25 mM | 0.1579 mL | 0.7895 mL | 1.5789 mL | 3.9473 mL | |
| 30 mM | 0.1316 mL | 0.6579 mL | 1.3158 mL | 3.2894 mL |