Ranatensin
Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212),Bradykinin (HY-P0206), or Norepinephrine (HY-13715).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 29451-71-6
- 分子式: C61H84N16O13S
- 分子量:1281.48
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
![[Tyr4]-Bombesin](https://file.medchemexpress.com/product_pic/hy-w343750.gif)
生物活性
Ranatensin (0.3 nM; 30 min) induces amylase release by various pancreatic secretagogues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ranatensin (10-50 μg/mL, 0.1-1 mL; i.v.; single dose) also lowers blood pressure in the monkey, being as potent as Eledoisin (HY-P0006). It show a direct peripheral action on vascular smooth muscle[2].
Ranatensin (10-50 μg/mL, 0.005-0.1 mL; i.v.; single dose) has a variable effect based on the basal level of blood pressure in the rat that shows antihypertensive efffect during high level and raises blood pressure when level is low, in part due to the release of noradrenaline from peripheral sympathetic nerve endings[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 29451-71-6
-
分子量 1281.48
-
分子式 C61H84N16O13S
-
シーケンスの短縮
Glp-VPQWAVGHFM-NH2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Jensen RT, et al. A synthetic peptide that is a bombesin receptor antagonist. Nature. 1984 May 3-9;309(5963):61-3. [Content Brief]
[2]. Geller RG, et al. The action of ranatensin, a new polypeptide from amphibian skin, on the blood pressure of experimental animals. Br J Pharmacol. 1970 Dec;40(4):605-16. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Ranatensin 関連分類
HY-P1685 関連分類
Powered by Bioz