SC 34301
SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 81026-63-3
- 分子式: C22H36O5
- 分子量:380.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice (E. coli, burned)[1]
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Dosage:200 µg/kg
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Administration:P.o.; once a day for three days
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Result:Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
化学情報
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CAS 番号 81026-63-3
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分子量 380.52
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分子式 C22H36O5
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SMILES
CCCCC(C)(O)C/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CC/C=C\CCC(OC)=O
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別名
Enisoprost
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [Content Brief]
[2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)