2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

製品番号: HY-110020
CAS 番号: 851320-29-1
Target:  

Cannabinoid Receptor

研究分野:  

Metabolic Disease

rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1 receptor antagonist. rel-O-2050 also decreases food intake in mice .
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製品番号: HY-111308
CAS 番号: 847554-50-1
研究分野:  

Neurological Disease

RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration .
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製品番号: HY-117805
CAS 番号: 177847-28-8
Target:  

Angiotensin Receptor

研究分野:  

Cardiovascular Disease

UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow .
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製品番号: HY-119926
CAS 番号: 15358-48-2
別名: Hydroxylupanine
Target:  

Integrin

13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
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製品番号: HY-119926A
CAS 番号: 6809-89-8
別名: Hydroxylupanine hydrochloride
13-Hydroxylupanine Hydroxylupanine is the typical alkaloid profile of sweet lupins. 13-Hydroxylupanine Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
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製品番号: HY-122101
CAS 番号: 17392-79-9
Target:  

JAK Apoptosis

研究分野:  

Cancer

NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5 .
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製品番号: HY-126852
CAS 番号: 163217-70-7
別名: P-Hydroxyatorvastatin lactone; 4-ATL
4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
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製品番号: HY-136676
CAS 番号: 122088-76-0
Target:  

Renin

研究分野:  

Cancer

Cgp 38560 methanesulfonate is a well-tolerated renin inhibitor. Cgp 38560 methanesulfonate caused a dose-dependent decrease in angiotensin II and plasma renin activity, and a dose-dependent increase in active renin.
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製品番号: HY-147327
CAS 番号: 26367-45-3
Target:  

Drug Metabolite

研究分野:  

Cancer

N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research .
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製品番号: HY-158329
CAS 番号: 561022-65-9
純度:  98.40%
別名: N-Alloc doxorubicin
Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth .
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製品番号: HY-163279
CAS 番号: 885902-66-9
Target:  

Glycosidase

研究分野:  

Others

Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings .
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製品番号: HY-179114
CAS 番号: 1211788-57-6
研究分野:  

Others

VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs .
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製品番号: HY-180958
CAS 番号: 3104316-26-6
Target:  

PROTACs

研究分野:  

Others

Chlorohexane-PEG-clozapine is a HaloTag PROTAC degrader based on Clozapine (HY-14539). Chlorohexane-PEG-clozapine leads to a significant decrease in the luminescence intensity and protein level of Halo-Eluc .
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製品番号: HY-B0606A
CAS 番号: 59985-21-6
別名: INS365 free base
Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye .
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製品番号: HY-N7646
CAS 番号: 143601-09-6
Curculigoside B, a phenolic glycoside isolated from Curculigo orchioides, enhances the osteoblast proliferation, decreases the area of bone resorption pit, osteoclastic formation and TRAP activity. Antiosteoporotic and antioxidative activities .
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製品番号: HY-P3637
CAS 番号: 2640019-27-6
Target:  

阻害性抗体

研究分野:  

Inflammation/Immunology

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG promotes bone-ossification. AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG can be used in the research of diseases or disorders related to osteogenic defects or bone mineral density (BMD) decreasing, such as osteoporosis .
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製品番号: HY-P99627
CAS 番号: 1708936-80-4
別名: NV-02; PG110; ABT-110

Target:  

Trk Receptor

研究分野:  

Inflammation/Immunology

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .
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製品番号: HY-116953
CAS 番号: 98049-69-5
別名: LXB4
Target:  

Endogenous Metabolite

研究分野:  

Inflammation/Immunology

Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
The product specifications provided below refer solely to the active content of Lipoxin B4.
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製品番号: HY-120152
CAS 番号: 1449765-82-5
SLP7111228 is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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製品番号: HY-120152A
CAS 番号: 1449768-48-2
純度:  98.0%
SLP7111228 hydrochloride is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 hydrochloride selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 hydrochloride decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 hydrochloride alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 hydrochloride can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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