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製品番号: HY-123453

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SM27

Name: SM27
Brand: MedChemExpress
SKU: HY-123453
Price: 299.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(別名: NSC 37204)

SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 6266-54-2
分子式: C₂₁H₁₆N₂O₉S₂
分子量:504.49

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

SM27 構造式

CAS 番号: 6266-54-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation^[1].

体外実験

SM27 (0-100 μM, 2 h) inhibits FGF2/heparin and FGF2/ FGFR1 interaction in a dose-dependent way with IC₅₀s of 3.5 and 4 mM, through inhibition of FGF2-mediated cell-cell adhesion with IC₅₀ of 1 mM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

化学情報

CAS 番号 6266-54-2
分子量 504.49
分子式 C₂₁H₁₆N₂O₉S₂
SMILES

O=S(C1=CC(O)=C2C=C(C=CC2=C1)NC(NC3=CC=C4C=C(C=C(C4=C3)O)S(=O)(O)=O)=O)(O)=O
別名

NSC 37204
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (266 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Pagano K, et al., Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule. PLoS One. 2012;7(5):e36990. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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