Sorbitan monopalmitate
Based on 1 Customer Validation
Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 26266-57-9
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保管条件:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
生物活性
Sorbitan monopalmitate (0-5% w/w; 30 min) modulates the color properties of mango butter formulations. Compared with the group supplemented with 1% w/w Sorbitan monopalmitate, supplementation with 5% w/w Sorbitan monopalmitate reduces yellowness and increases whiteness[2].
Sorbitan monopalmitate (1-5% w/w; 30 min) promotes the aggregation of spherical mango fat crystals and forms a denser fat crystal network, thereby modulating the crystal structure of mango fat[2].
Sorbitan monopalmitate (1-5% w/w; 5 h) improves the mechanical stability of mango butter formulations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:(male) rat[1]
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Dosage:2,250 mg/kg bw per day
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Administration:p.o.; continuous daily feeding via diet; 2 years
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Result:Showed no alterations in growth pattern or survival compared to controls.
Found no abnormalities attributable to the experimental diet in blood studies or histopathological examination of the brain, spleen, pancreas, adrenal gland, bladder, bone marrow, heart, lymph nodes, lung, testicle, or muscle.
化学情報
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CAS 番号 26266-57-9
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性状 Solid
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Color White to off-white
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SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
溶剤 & 溶解度
Ethanol : 50 mg/mL (Need ultrasonic)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (394 KB)
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- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), et al. Re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. EFSA J. 2017;15(5):e04788. Published 2017 May 5. [Content Brief]
[2]. Das P, et al. Effect of sorbitan monopalmitate on the polymorphic transitions and physicochemical properties of mango butter. Food Chem. 2021;347:128987. [Content Brief]
[3]. Varshosaz J, et al. Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. Drug Deliv. 2005;12(2):75-82. [Content Brief]
[4]. BELL JT Jr, et al. Polyoxyethylene sorbitan monopalmitate (tween 40) as a vehicle for oil red O fat stain. Stain Technol. 1959 Jul;34(4):219-21. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)