country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-B0767

Copy Link Print Information

Spinosyn A

カスタマーレビュー

Based on 1 Customer Validation

Spinosyn A, a polyketide-derived macrolide produced by Saccharopolyspora spinosa, is a potent insecticide.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.93%
CAS 番号: 131929-60-7
分子式: C₄₁H₆₅NO₁₀
分子量:731.96

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Spinosyn A 構造式

CAS 番号: 131929-60-7

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Spinosyn A, a polyketide-derived macrolide produced by Saccharopolyspora spinosa, is a potent insecticide^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	10.7 μM Compound: 1	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 30201293]
HCT-116	IC₅₀	11.1 μM Compound: 1	Antiproliferative activity against human HCT116 cells incubated for 48 hrs Antiproliferative activity against human HCT116 cells incubated for 48 hrs	[PMID: 32139325]
HT-29	IC₅₀	7.3 μM Compound: SPA	Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 37682035]
MCF7	IC₅₀	16.7 μM Compound: 1	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30201293]
MCF7	IC₅₀	17.9 μM Compound: 1	Antiproliferative activity against human MCF7 cells incubated for 48 hrs Antiproliferative activity against human MCF7 cells incubated for 48 hrs	[PMID: 32139325]
NCI-H460	IC₅₀	66 μM Compound: 1	Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 30201293]
NCI-H460	IC₅₀	67.5 μM Compound: 1	Antiproliferative activity against human NCI-H460 cells incubated for 48 hrs Antiproliferative activity against human NCI-H460 cells incubated for 48 hrs	[PMID: 32139325]
RKO	IC₅₀	17 μM Compound: SPA	Antiproliferative activity against human RKO cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human RKO cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 37682035]
U-87MG ATCC	IC₅₀	103.8 μM Compound: 1	Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay	[PMID: 30201293]
U-87MG ATCC	IC₅₀	96.5 μM Compound: 1	Antiproliferative activity against human U87MG cells incubated for 48 hrs Antiproliferative activity against human U87MG cells incubated for 48 hrs	[PMID: 32139325]

体外実験

Spinosad is a mixture of two natural occurring macrocyclic lactones (spinosyn A and spinosyn D) and acts primarily as a nAChR agonist^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 131929-60-7
性状 Solid
分子量 731.96
分子式 C₄₁H₆₅NO₁₀
Color White to off-white
SMILES

O=C([C@@H]([C@H](CCC[C@@H](O1)CC)O[C@@H]2O[C@@H]([C@H](CC2)N(C)C)C)C)C3=C[C@@]([C@](C=C[C@]4([H])C5)([H])[C@]3([H])CC1=O)([H])[C@]4([H])C[C@@H]5O[C@H]6[C@@H]([C@@H]([C@H]([C@@H](O6)C)OC)OC)OC
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Saccharopolyspora spinosa
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : ≥ 100 mg/mL (136.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.3662 mL

6.8310 mL

13.6619 mL

5 mM

0.2732 mL

1.3662 mL

2.7324 mL

10 mM

0.1366 mL

0.6831 mL

1.3662 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (274 KB)
SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Hak Joong Kim, et al. Biosynthesis of spinosyn in Saccharopolyspora spinosa: synthesis of permethylated rhamnose and characterization of the functions of SpnH, SpnI, and SpnK. J Am Chem Soc. 2010 Mar 10;132(9):2901-3. [Content Brief]

[2]. D T Vo, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33(4):315-22. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.3662 mL	6.8310 mL	13.6619 mL	34.1549 mL
	5 mM	0.2732 mL	1.3662 mL	2.7324 mL	6.8310 mL
	10 mM	0.1366 mL	0.6831 mL	1.3662 mL	3.4155 mL
	15 mM	0.0911 mL	0.4554 mL	0.9108 mL	2.2770 mL
	20 mM	0.0683 mL	0.3415 mL	0.6831 mL	1.7077 mL
	25 mM	0.0546 mL	0.2732 mL	0.5465 mL	1.3662 mL
	30 mM	0.0455 mL	0.2277 mL	0.4554 mL	1.1385 mL
	40 mM	0.0342 mL	0.1708 mL	0.3415 mL	0.8539 mL
	50 mM	0.0273 mL	0.1366 mL	0.2732 mL	0.6831 mL
	60 mM	0.0228 mL	0.1138 mL	0.2277 mL	0.5692 mL
	80 mM	0.0171 mL	0.0854 mL	0.1708 mL	0.4269 mL
	100 mM	0.0137 mL	0.0683 mL	0.1366 mL	0.3415 mL

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ

Amount: USD 0.00

生物活性
- 製品説明
- 体外実験
化学情報
溶剤 & 溶解度
- 体外実験
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

Spinosyn A

Natural Product Library

Glycoside Compound Library

Microbial Metabolite Library

Anti-Pulmonary Fibrosis Compound Library

Heterocyclic Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

Pesticide Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Bacteria-Sourced Compound Library

Mass Spectrometry Natural Product Library

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Spinosyn A

Natural Product Library

Glycoside Compound Library

Microbial Metabolite Library

Anti-Pulmonary Fibrosis Compound Library

Heterocyclic Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

Pesticide Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Bacteria-Sourced Compound Library

Mass Spectrometry Natural Product Library

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Spinosyn A 関連分類

HY-B0767 関連分類