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TAPI-1 (Standard)

TAPI-1 (Standard) is the analytical standard of TAPI-1 (HY-16657). This product is intended for research and analytical applications. TAPI-1 is a broad-spectrum MMP inhibitor and NF-κB p65 inhibitor that targets ADAM17/TACE, ADAM10 and other proteins. TAPI-1 reduces the proteolytic cleavage of membrane-bound TNF-α, decreases TNF-α levels, inhibits NF-κB pathway activation, and downregulates profibrotic markers. TAPI-1 reduces the proportion of proinflammatory immune cells, alleviates cardiac and airway fibrosis, and improves cardiac function after myocardial infarction. Meanwhile, TAPI-1 inhibits the viability, migration and invasion of esophageal squamous cell carcinoma cells, enhances the chemosensitivity of Cisplatin (HY-17394), induces apoptosis, and shows low toxicity to normal esophageal epithelial cells. TAPI-1 can be widely used in studies related to myocardial infarction-induced heart failure, severe traumatic tracheal stenosis, esophageal squamous cell carcinoma and other conditions.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • CAS 番号: 163847-77-6
  • 分子式: C26H37N5O5
  • 分子量:499.60
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • TAPI-1 (Standard) Chemical Structure
    TAPI-1 (Standard) 構造式
CAS 番号: 163847-77-6
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  • TAPI-1 (Standard) Chemical Structure
    TAPI-1 (Standard) Chemical Structure
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  • TAPI-1 (Standard)