Uracil-13C4
Based on 1 Customer Validation
Uracil-13C4 is the 13C labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.88%
- 分子式: 13C4H4N2O2
- 分子量:116.04
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 66-22-8
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性状 Solid
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分子量 116.04
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分子式 13C4H4N2O2
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Color White to off-white
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SMILES
O=[13C]1[13C]=[13C]N[13C](N1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 25 mg/mL (215.44 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Pałasz A, et al. In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications. Eur J Med Chem. 2015 Jun 5;97:582-611. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.6177 mL | 43.0886 mL | 86.1772 mL | 215.4429 mL |
| 5 mM | 1.7235 mL | 8.6177 mL | 17.2354 mL | 43.0886 mL | |
| 10 mM | 0.8618 mL | 4.3089 mL | 8.6177 mL | 21.5443 mL | |
| 15 mM | 0.5745 mL | 2.8726 mL | 5.7451 mL | 14.3629 mL | |
| 20 mM | 0.4309 mL | 2.1544 mL | 4.3089 mL | 10.7721 mL | |
| 25 mM | 0.3447 mL | 1.7235 mL | 3.4471 mL | 8.6177 mL | |
| 30 mM | 0.2873 mL | 1.4363 mL | 2.8726 mL | 7.1814 mL | |
| 40 mM | 0.2154 mL | 1.0772 mL | 2.1544 mL | 5.3861 mL | |
| 50 mM | 0.1724 mL | 0.8618 mL | 1.7235 mL | 4.3089 mL | |
| 60 mM | 0.1436 mL | 0.7181 mL | 1.4363 mL | 3.5907 mL | |
| 80 mM | 0.1077 mL | 0.5386 mL | 1.0772 mL | 2.6930 mL | |
| 100 mM | 0.0862 mL | 0.4309 mL | 0.8618 mL | 2.1544 mL |
Uracil-13C4 関連分類
HY-I0960S1 関連分類
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